Diagnosis and treatment of peripheral neuropathy induced by ANCA-associated vasculitis

ANCA-associated vasculitis is induced by necrotizing angiitis of small vessels supplying the peripheral nervous system. Ischemic processes induce neuronal damage and axonal degeneration in the peripheral nerve. Motor dysfunction as well as sensory disturbance and allodynia caused by neuropathic symp...

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Bibliographic Details
Published inBrain and nerve = Shinkei kenkyū no shinpo Vol. 66; no. 7; p. 857
Main Author Hattori, Naoki
Format Journal Article
LanguageJapanese
Published Japan 01.07.2014
Subjects
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - complications
Humans
Peripheral Nervous System Diseases - diagnosis
Peripheral Nervous System Diseases - etiology
Peripheral Nervous System Diseases - therapy
Prognosis
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Summary:ANCA-associated vasculitis is induced by necrotizing angiitis of small vessels supplying the peripheral nervous system. Ischemic processes induce neuronal damage and axonal degeneration in the peripheral nerve. Motor dysfunction as well as sensory disturbance and allodynia caused by neuropathic symptoms may influence an individual's activities of daily living and quality of life. Notably, the peripheral nerve is predominantly affected in ANCA-associated vasculitis. We suggest that early diagnosis and appropriate treatment are important to improve survival in and functional prognosis of ANCA-associated vasculitis.
ISSN:1881-6096