Clinical manifestations of 10 cases of imported human Zika virus disease in Jiangmen city of China

• Published in: Zhong hua yi xue za zhi Vol. 96; no. 45; p. 3666
• Main Authors: Zheng, N C, Liu, Y H, Chen, Q, Chen, M T, Zheng, C G, Yang, Z W, Hu, J, Liang, J H, Xue, M H, Chen, A Q, Feng, Q W
• Format: Journal Article
• Language: Chinese
• Published: China 06.12.2016
• Subjects: China; Drug Eruptions; Fever; Humans; Saliva; Zika Virus; Zika Virus Infection
• ISSN: 0376-2491
• DOI: 10.3760/cma.j.issn.0376-2491.2016.45.012

To study the clinical manifestations and detection method for imported patients of Zika virus disease. The records of symptoms, signs and laboratory results were collected and analyzed. The specimen of blood, saliva and urine from patients were collected. Two of ten patients had mild fever. The visible cutaneous maculopapular rash of the trunk and extremities was observed in all patients. Seven patients were observed congestive conjunctivitis and only one patient gave an account of itching. No patient had symptoms of myalgia or arthralgia. The laboratory results of patients were normal except two patients had mild leucopenia and another one had thrombocytosis. The Zika virus RNA was detected in urine samples for a longest period. The detection rates of Zika virus RNA from the samples of blood, saliva and urine that collected in seventh day after disease onset were 0, 5, 8 cases, respectively. Epidemiology history, maculopapular rash, congestive conjunctivitis and Zika virus RNA being detected in urine can be