Gender-dependent Expression of ERβ in AEC Ⅱ of Fetal Mice Exposed to Arsenic and Estrogen Receptor Antagonist

• Published in: Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban Vol. 49; no. 3; p. 364
• Main Authors: Yang, Meng-Ping, Che, Wang-Jun, Cheng, Ya-Ling, Xiong, Lin-Sen, Zhang, Hao
• Format: Journal Article
• Language: Chinese
• Published: China 01.05.2018
• Subjects: Alveolar Epithelial Cells - drug effects; Alveolar Epithelial Cells - metabolism; Animals; Apoptosis; Arsenic - toxicity; Estrogen Receptor alpha; Estrogen Receptor Antagonists - toxicity; Estrogen Receptor beta - metabolism; Female; Male; Mice; Mice, Inbred ICR; Pregnancy; Sex Factors; Estrogen receptor β; Estrogen receptor antagonist; Fetal mice; Sodium arsenite; AEC

To determine the effects of arsenic and estrogen receptor antagonist (ICI182, 780) on the expression of estrogen receptor beta (ERβ) in alveolar Ⅱ epithelial cells (AECⅡ) of female and male mice. Nineteen or twenty day fetus mice were obtained through caesarean section of ICR mice. Purified AECⅡ cel...