Clinical predictors of cytomegalovirus infection after liver transplantation

• Published in: Chung-hua wai kʿo tsa chih Vol. 53; no. 4; p. 270
• Main Authors: Kou, Jiantao, Zhu, Jiqiao, Fan, Hua, Ma, Jun, Li, Ping, Han, Dongdong, He, Qiang
• Format: Journal Article
• Language: Chinese
• Published: China 01.04.2015
• Subjects: Adult; Beijing; Cytomegalovirus Infections - diagnosis; End Stage Liver Disease - diagnosis; Female; Graft Rejection; Humans; Liver Transplantation - adverse effects; Logistic Models; Male; Middle Aged; Multivariate Analysis; Postoperative Complications - virology; Reoperation; Retrospective Studies; Severity of Illness Index; Beijing
• ISSN: 0529-5815

To investigate the clinical predictors of cytomegalovirus (CMV) infection after liver transplantation. The clinical data of 182 patients (146 male and 36 female with a mean age of (50 ± 7) years) receiving liver transplantation in Beijing Chaoyang Hospital between January 2004 and December 2008 were retrospectively analyzed.All patients were divided into two groups, namely the CMV infection group (n=24) and the control group (n=158). Logistic regression was used to identify the predictive factors of postoperative CMV infection. According to univariate analysis results, the factors for CMV infection were acute liver failure (P=0.032), MELD score ≥ 30 (P=0.001), liver retransplantation (P=0.002), acute rejection (P=0.000) and delayed graft function (P=0.022). According to multi-analysis results, MELD score ≥ 30 (P=0.037, 95%CI:1.194-271.461) and acute rejection (P=0.033, 95%CI:1.179-51.863) were proved to be independent predictors by multivariate analysis. The study indicates that MELD score ≥ 30 and acute reje