Indications for invasive prenatal diagnostic procedures at a dedicated fetal medicine centre: an 8 year audit 2003-2010

Analyze indications and type of prenatal diagnostic procedures performed. This retrospective audit was conducted at a dedicated fetal medicine center in Petaling Jaya. All invasive prenatal diagnosis procedures performed from 2003 up until 2010 (amniocentesis, chorionic villous sampling and fetal bl...

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Published inMedical journal of Malaysia Vol. 68; no. 4; pp. 297 - 300
Main Authors Valayatham, Vijayan, Subramaniam, Raman, Juan, Yap Moy, Chia, Patrick
Format Journal Article
LanguageEnglish
Published Malaysia 01.08.2013
Subjects
Amniocentesis
Chorionic Villi Sampling
Humans
Maternal Age
Prenatal Diagnosis
Retrospective Studies
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Summary:Analyze indications and type of prenatal diagnostic procedures performed. This retrospective audit was conducted at a dedicated fetal medicine center in Petaling Jaya. All invasive prenatal diagnosis procedures performed from 2003 up until 2010 (amniocentesis, chorionic villous sampling and fetal blood sampling) were analyzed. A total of 1560 invasive prenatal diagnostic procedures were performed during the 8 year period. Advanced maternal age is the leading indication for invasive prenatal diagnostic procedures followed by fetal abnormalities. The fetal loss rate was 0.2% for amniocentesis and 1.2% for CVS. Advanced maternal age is the leading indication for invasive prenatal diagnostic procedures at this centre but is on a declining trend. The fetal loss rates are comparable to auditable standards set by professional bodies, in this case, the Royal College of Obstetricians & Gynecologists of London.
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ISSN:0300-5283