Risk factors for acute respiratory syncytial virus infection of lower respiratory tract in hospitalized infants

To investigate the clinical epidemiologic characteristics and analyze risk factors for acute respiratory syncytial virus (RSV) infection in hospitalized infants with acute lower respiratory tract infection (ALRI). ALRI infants admitted to Children's Hospital of Fudan University from March 1st,...

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Published inZhonghua er ke za zhi Vol. 52; no. 5; p. 373
Main Authors Zhang, Xiaobo, Liu, Lijuan, Shi, Peng, Jiang, Gaoli, Jia, Pin, Wang, Chuankai, Wang, Libo, Qian, Liling
Format Journal Article
LanguageChinese
Published China 01.05.2014
Subjects
Acute Disease
China - epidemiology
Environmental Exposure - adverse effects
Female
Hospitalization - statistics & numerical data
Humans
Infant
Infant, Newborn
Logistic Models
Male
Prevalence
Respiratory Syncytial Virus Infections - epidemiology
Respiratory Syncytial Virus Infections - prevention & control
Respiratory Syncytial Virus, Human - isolation & purification
Respiratory Tract Infections - epidemiology
Respiratory Tract Infections - prevention & control
Respiratory Tract Infections - virology
Retrospective Studies
Risk Factors
Seasons
Socioeconomic Factors
Tobacco Smoke Pollution
China
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Summary:To investigate the clinical epidemiologic characteristics and analyze risk factors for acute respiratory syncytial virus (RSV) infection in hospitalized infants with acute lower respiratory tract infection (ALRI). ALRI infants admitted to Children's Hospital of Fudan University from March 1st, 2011 to February 29th, 2012, were enrolled in this study. Patient information included demographic characteristics, feeding history, family status, clinical presentation, accessory examination, treatment and prognosis. According to the etiology of ALRI infants, we compared the seasonal distribution, demographic characteristics, household characteristics and underlying diseases between RSV-positive patients and RSV-negative patients. Univariate and multiple Logistic regression analyses were used to determine factors that were associated with risk of RSV infection. Among 1 726 ALRI infants, there were 913 RSV-positive infants (52.9%). The occurrence of RSV infection had a seasonal variation, with a peak in winter (59.1%).
ISSN:0578-1310