A case of metachronous ovarian metastasis after curative surgery of colon cancer with simultaneous hepatic metastasis

• Published in: Gan to kagaku ryoho Vol. 40; no. 12; p. 1927
• Main Authors: Eto, Eiichi, Ito, Yasuhiro, Mihara, Koki, Nishiya, Shin, Shibutani, Shintaro, Egawa, Tomohisa, Hayashi, Shinobu, Nagashima, Atsushi
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.11.2013
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Chemotherapy, Adjuvant; Colonic Neoplasms - drug therapy; Colonic Neoplasms - pathology; Colonic Neoplasms - surgery; Female; Hepatectomy; Humans; Liver Neoplasms - drug therapy; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Middle Aged; Ovarian Neoplasms - secondary; Ovarian Neoplasms - surgery; Time Factors
• ISSN: 0385-0684

The patient was a 51-year-old woman who presented with nausea, vomiting, and abdominal pain. Detailed examination revealed a carcinoma of the descending colon with simultaneous hepatic metastasis. Because the carcinoma comprised a circumferential stenotic lesion and resection of the hepatic metastasis was feasible, combined left hemicolectomy and hepatectomy were initially performed. During postoperative adjuvant chemotherapy, the hepatic metastasis was observed to increase in size, and therefore, a second hepatectomy was performed approximately 2 years and 6 months after the initial surgery. Adjuvant chemotherapy was subsequently continued for approximately 1 year. A metastatic ovarian tumor was identified on abdominal computed tomography (CT) approximately 1 year after chemotherapy was discontinued. Bilateral salpingo-oophorectomy was performed approximately 3 years and 6 months after the initial surgery. Histopathological examination revealed the lesion to be a colon carcinoma metastasis.