An experimental study on rabbit liver by 3.0 Tesla magnetic resonance diffusion-weighted imaging

• Published in: Zhōngguó yīxué kēxuéyuàn xuébào Vol. 34; no. 1; p. 51
• Main Authors: Dong, Tian-Ming, Sun, Xi-Jie, Xu, Xian, Dai, Jing, Zheng, Wei, An, Ning-Yu, Wang, Xiao-Qing
• Format: Journal Article
• Language: Chinese
• Published: China 01.02.2012
• Subjects: Animals; Diffusion Magnetic Resonance Imaging - methods; Liver; Male; Rabbits
• ISSN: 1000-503X
• DOI: 10.3881/j.issn.1000-503X.2012.01.010

To explore the methodology as well as the features, quantificational index, and reference standard of 3.0 Tesla magnetic resonance (MR) diffusion-weighted imaging (DWI) on the normal rabbit's liver. Twenty New Zealand white rabbits were enrolled and DWI was performed after anesthetics with multi-b values at 3.0 T MR scanner. Apparent diffusion coefficient (ADC) values as well as the difference between maximum and minimum ADC values, signal strength (SH), noise signal (SD), signal to noise ratio (SNR), and quality index (QI) were recorded and analyzed. With b value increased, the ADC values decreased accordingly (P < 0.001). The difference between maximum and minimum ADC values with b = 1000 s/mm2 was the least (good stability), b = 600 s/mm2 was the second least, and b = 300 s/mm2 was greatest (bad stability). The SH decreased at the same time (P < 0.001), but the difference among DWI with b =600, 800, and 1000 s/mm2 was not statistically significant (P > 0.05). The SD decreased at the same time (P < 0.001),