Malignant Pleural Mesothelioma Presenting Refractory Pneumothorax Successfully Treated by Intrapleural Administration of Diluted Fibrin Glue;Report of a Case

Malignant pleural mesothelioma sometimes accompanies intractable neumothorax due to the visceral pleural invasion of the tumor. A 68-years-old man was found to have massive pleural effusion and pleural mass combined with pneumothorax by computed tomography(CT). CT guided biopsy revealed the mass to...

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Published inKyobu geka. The Japanese journal of thoracic surgery Vol. 70; no. 5; p. 393
Main Authors Nishino, Takeshi, Takizawa, Hiromitsu, Nishioka, Kohei, Fujimoto, Keisuke, Miyamoto, Naoki, Aoyama, Mariko, Sawada, Toru, Kawakita, Naoya, Kajiura, Koichiro, Toba, Hiroaki, Kawakami, Yukikiyo, Yoshida, Mitsuteru
Format Journal Article
LanguageJapanese
Published Japan 01.05.2017
Subjects
Aged
Biopsy
Drainage
Fatal Outcome
Fibrin Tissue Adhesive - therapeutic use
Humans
Lung Neoplasms - complications
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - pathology
Male
Mesothelioma - complications
Mesothelioma - diagnostic imaging
Mesothelioma - pathology
Mesothelioma, Malignant
Pneumothorax - diagnostic imaging
Pneumothorax - etiology
Pneumothorax - therapy
Recurrence
Tissue Adhesives - therapeutic use
Tomography, X-Ray Computed
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Summary:Malignant pleural mesothelioma sometimes accompanies intractable neumothorax due to the visceral pleural invasion of the tumor. A 68-years-old man was found to have massive pleural effusion and pleural mass combined with pneumothorax by computed tomography(CT). CT guided biopsy revealed the mass to be malignant pleural mesothelioma. Since continuous air leakage was observed by chest drainage, pleurodesis by OK-432 twice and bronchial occlusion by Endobronchial Watanabe Spigot (EWS)were performed. But air leakage continued, and the surgery was performed, however the treatment failed to stop the air leakage. Finally, the intrapleural administration of diluted fibrin glue was challenged and the air leakage stopped immediately after the treatment.
ISSN:0021-5252