Development of Hf(4+)-immobilized polydopamine-coated magnetic graphene for highly selective enrichment of phosphopeptides

• Published in: Talanta (Oxford) Vol. 149; pp. 91 - 97
• Main Authors: Lin, Haizhu, Deng, Chunhui
• Format: Journal Article
• Language: English
• Published: Netherlands 2016
• Subjects: Animals; Caseins - chemistry; Graphite - chemistry; Hafnium - chemistry; Humans; Indoles - chemistry; Magnetic Phenomena; Milk - chemistry; Phosphopeptides - chemistry; Polymers - chemistry; Serum - chemistry; Serum Albumin, Bovine - chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Polydopamine; IMAC; Phosphopeptides enrichment; MALDI; Hafnium

In this work, we first designed and synthesized an IMAC material with Hf(4+) immobilized on polydopamine-coated magnetic graphene and applied it to phosphopeptides enrichment successfully. The newly prepared material gathered the advantages of large specific surface area of graphene, good hydrophili...