Nagelamide I and 2,2'-didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge Agelas sp

New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric...

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Published inChemical & pharmaceutical bulletin Vol. 62; no. 2; p. 213
Main Authors Iwai, Takahiro, Kubota, Takaaki, Fromont, Jane, Kobayashi, Jun'ichi
Format Journal Article
LanguageEnglish
Published Japan 2014
Subjects
Agelas - chemistry
Alkaloids - chemistry
Alkaloids - isolation & purification
Animals
Halogenation
Imidazoles - chemistry
Imidazoles - isolation & purification
Pyrroles - chemistry
Pyrroles - isolation & purification
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Abstract New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole-imidazole alkaloid consisting of two subunits connected with a single bond.
AbstractList New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole-imidazole alkaloid consisting of two subunits connected with a single bond.New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole-imidazole alkaloid consisting of two subunits connected with a single bond.
New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole-imidazole alkaloid consisting of two subunits connected with a single bond.
Author Kubota, Takaaki
Kobayashi, Jun'ichi
Fromont, Jane
Iwai, Takahiro
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  fullname: Kobayashi, Jun'ichi
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Snippet New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2'-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas...
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StartPage 213
SubjectTerms Agelas - chemistry
Alkaloids - chemistry
Alkaloids - isolation & purification
Animals
Halogenation
Imidazoles - chemistry
Imidazoles - isolation & purification
Pyrroles - chemistry
Pyrroles - isolation & purification
Title Nagelamide I and 2,2'-didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge Agelas sp
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Volume 62
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