Impact of baseline pulse pressure on new-onset cardio-and cerebrovascular events in diabetic population

• Published in: Zhōnghuá xīnxuèguănbìng zázhi Vol. 41; no. 6; p. 514
• Main Authors: Liu, Xiu-rong, Wu, Shou-ling, Wang, Li-ye, Su, Li-rong, Cao, Zheng-xin, Zhou, Yan-ru, Sun, Ya-hui, Sun, Yue-qiu, Liu, Li-ying
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2013
• Subjects: Adult; Aged; Aged, 80 and over; Blood Pressure - physiology; Cardiovascular Diseases - etiology; Diabetes Mellitus - physiopathology; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Young Adult
• ISSN: 0253-3758
• DOI: 10.3760/cma.j.issn.0253-3758.2013.06.016

To observe the association between baseline pulse pressure (PP) level and new-onset cardio-cerebrovascular events in diabetic population. Physical examination data between July 2006 to October 2007 from a total of 101 510 employees of Kailuan Group were reviewed, 8306 subjects with a fasting plasma glucose level of ≥ 7.0 mmol/L or with confirmed diabetes diagnosis and were enrolled in this prospective cohort study. Subjects were followed up for 38-53 (48.1 ± 3.1) months and the cardio-cerebrovascular events were obtained every six months, association between baseline PP and new-onset cardio-cerebrovascular events in the diabetic population were analyzed. (1) Incidences of total cardio-cerebrovascular events in the PP groups were 3.4%, 2.8%, 4.5%, 6.4%, respectively. Incidences of cerebral infarction events and myocardial infarction were 2.1%, 1.6%, 2.9%, 3.9% and 1.1%, 0.7%, 1.0%, 1.7%, respectively. (2) Multivariate Cox's proportional hazards regression analysis indicated that baseline PP group was the risk