Ovarian metastases of pancreatic ductal adenocarcinomas: the clinicopathological characteristics and outcomes of 10 cases

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 42; no. 4; pp. 331 - 335
• Main Authors: Wang, X, You, Y, Ge, Y P, Ying, H Y, Cheng, Y J, Bai, C M
• Format: Journal Article
• Language: Chinese
• Published: China 23.04.2020
• Subjects: Ovarian metastases; Prognosis; Clinicopathological feature; Pancreatic neoplasms
• ISSN: 0253-3766
• DOI: 10.3760/cma.j.cn112152-20190220-00100

To investigate the clinicopathological characteristics and outcomes of a series of ovarian metastases of pancreatic ductal adenocarcinoma. Data of clinical manifestation, pathological characteristic, treatment and follow-up result from ten patients with ovarian metastases of pancreatic ductal adenocarcinoma confirmed by pathology were retrospectively analyzed. The median age of onset was 46 years (38~79 years). The primary tumors were located in the body and tail of the pancreas in 8 cases. Bilateral ovarian metastasis occurred in 8 patients at the time of diagnosis. The median time from patients with clinical symptom to ovarian metastases was 2.5 months (0~12 months). Peritoneal metastasis was found in all of 10 cases. Nine cases were accompanied by CA125 elevation. The major features of metastatic carcinoma in the ovary were cystic-solid appearance (8 cases) and mucinous adenocarcinoma (6 cases) with no obvious immunohistochemical features in pathological observation. All patients underwent palliative ovari