Predictive value of tumor vessel density from enhanced spiral CT scan for lymph node and distant metastasis of colorectal cancer

To test whether the tumor vessel density (TVD) from the enhanced spiral CT can preoperatively predict nodal status and distant metastasis of colorectal cancer. Forty cases of colorectal cancer patients who received surgical treatment were included in this study. The three dimensional tumor vessels w...

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Published inZhonghua wei chang wai ke za zhi Vol. 16; no. 5; p. 448
Main Authors Jing, Yang, Sun, Li-Bo, Shu, Zhen-Bo, Li, Yong-Chao, Ding, Da-Yong, Zhang, Hui-Mao, Bo, Li-Hua
Format Journal Article
LanguageChinese
Published China 01.05.2013
Subjects
Colorectal Neoplasms
Humans
Lymph Nodes
Lymphatic Metastasis
Neoplasm Staging
Tomography, Spiral Computed
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Summary:To test whether the tumor vessel density (TVD) from the enhanced spiral CT can preoperatively predict nodal status and distant metastasis of colorectal cancer. Forty cases of colorectal cancer patients who received surgical treatment were included in this study. The three dimensional tumor vessels were reconstructed by an enhanced CT 64-slice spiral CT and its AW4.4 image processing platform. The TVD was measured by the 1000 high-resolution color graphics pathological analysis system. The TVD level was compared between different tumor size, classification, and TNM stage. The postoperative pathological staging was taken as golden standard. The sensitivity, specificity and accuracy for direct prediction of lymph node metastasis by the enhanced CT 64-slice spiral CT was 74.1%(20/27), 53.8%(7/13) and 67.5%(27/40) respectively. The TVD from the reconstructed three dimensional tumor vessels in the group with lymph node metastasis was significantly higher than that without metastasis(0.070±0.046 vs. 0.037±0.013, P<0
ISSN:1671-0274