Application of Microfluidics in Molecular Diagnostics

In recent years, molecular diagnostics has been the most promising branch of diagnosis(IVD) due to its high sensitivity and specificity. However, it's not suitable for the research of molecule with macroscopic tools. Microfluidics can achieve precise control of micro-fluid and has been widely a...

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Published inZhongguo yi liao qi xie za zhi Vol. 44; no. 6; p. 520
Main Authors Wang, Chao, Zhang, Dongfeng, Yang, Liuqing, Liu, Yaoji, Wu, Yue
Format Journal Article
LanguageChinese
Published China 08.12.2020
Subjects
Humans
Microfluidics
Molecular Diagnostic Techniques - instrumentation
Pathology, Molecular - instrumentation
molecular diagnositics
gene sequencing
microfluidics
PCR
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Summary:In recent years, molecular diagnostics has been the most promising branch of diagnosis(IVD) due to its high sensitivity and specificity. However, it's not suitable for the research of molecule with macroscopic tools. Microfluidics can achieve precise control of micro-fluid and has been widely applied in molecular diagnostics because of its advantages such as lower sample consumption, shorter reaction time, and easier to integrate. Molecular diagnostics has made great development in methodology and automatic integration based on microfluidics. In this paper, we introduce the applications of microfluidics in molecular diagnostics and analysis the challenges of it.
ISSN:1671-7104
DOI:10.3969/j.issn.1671-7104.2020.06.011