Experimental study on radiofrequency ablation technology for treatment of infected wounds in minipigs

• Published in: Zhongguo xiu fu chong jian wai ke za zhi Vol. 27; no. 9; p. 1110
• Main Authors: Yang, Rungong, Zuo, Tantan, Zhu, Jialiang, Zhong, Hongbin, Wu, Kejian, Hou, Shuxun
• Format: Journal Article
• Language: Chinese
• Published: China 01.09.2013
• Subjects: Animals; Catheter Ablation - methods; Colony Count, Microbial; Debridement - methods; Disease Models, Animal; Female; Male; Staphylococcal Skin Infections - microbiology; Staphylococcal Skin Infections - surgery; Swine; Swine, Miniature; Time Factors; Wound Healing; Wounds and Injuries - microbiology; Wounds and Injuries - surgery
• ISSN: 1002-1892

To observe the effect of radiofrequency ablation technology for the treatment of infected wounds in minipigs. Infected wounds of full-thickness skin defects (about 6.15 cm2/wound) were prepared in 8 6-month-old minipigs (weighing, 30-35 kg) using the method of Davis et al. The 160 wounds were randomly divided into 4 groups (n = 40). Infected wounds were debrided with the radiofrequency ablation technology in group A, with the electric knife in group B, and with the scalpel in group C; no treatment was done in group D as a control. The healing rate, healing time, and tissue filling rate were observed; bacterial quantitative examination and histological examination were done at 0, 2, 7, and 14 days after operation. All infected wounds were successfully established after 48 hours when Staphylococcus aureus dilution were inoculated. The wounds after radiofrequency ablation technology treatment were fresh and flat with slight bleeding; the healing time of group A was significantly shorter than that of groups B, C,