Impact and related mechanism of exogenous receptor activity modifying protein 1 on calcitonin gene-related peptide modified bone marrow mesenchymal stem cells on the migration of vascular smooth muscle cells in vitro

• Published in: Zhōnghuá xīnxuèguănbìng zázhì Vol. 43; no. 6; p. 537
• Main Authors: Long, Xianping, Cui, Can, Chen, Panke, Wang, Song, Wang, Dongmei, Xu, Guanxue, Yao, Xiaojian, Shi, Bei
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2015
• Subjects: Animals; Bone Marrow Cells; Calcitonin Gene-Related Peptide; Cell Movement; Coculture Techniques; Hematopoietic Stem Cells; In Vitro Techniques; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Rats; Receptor Activity-Modifying Protein 1; Signal Transduction; Transfection

To investigate the impact of calcitonin gene-related peptide (CGRP) modified bone marrow mesenchymal stem cell (MSC) on the migration of vascular smooth muscle cell (VSMC) and related mechanisms. The MSC and VSMC were isolated from rats and cultured, CGRP was transfected to MSC with the high express...