Pathophysiological and molecular mechanisms of extracellular matrix protein resorption during skin aging, and the ways to their restoration

The article is a short review of the most studied molecular mechanisms leading to skin aging. It considers mechanisms of cellular aging, oxidative stress, development of chronic inflammation, as well as synthesis and degradation of extracellular matrix proteins. The review also contains examples of...

Full description

Saved in:
Bibliographic Details
Published inPatologicheskaia fiziologiia i eksperimental'naia terapiia Vol. 60; no. 4; p. 128
Main Authors Gorkun, A A, Kozhina, K V, Zurina, I M, Kosheleva, N V, Saburina, I N
Format Journal Article
LanguageEnglish
Published Russia (Federation) 01.10.2016
Online AccessGet more information

Cover

More Information
Summary:The article is a short review of the most studied molecular mechanisms leading to skin aging. It considers mechanisms of cellular aging, oxidative stress, development of chronic inflammation, as well as synthesis and degradation of extracellular matrix proteins. The review also contains examples of extracellular matrix restoration using cell and pharmacological technologies.
ISSN:0031-2991