A Case of Inflammatory Breast Cancer with Very Severe Obesity

A 39-year-old woman with very sever obesity was admitted to our hospital for a right breast redness and hardness. Her height, weight and BMI were 166 cm, 145 kg and 52.6 kg/m2. Her breast had peau d'orange. CT scan showed swelling of whole right breast and Level I , II lymph node. We performed...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 44; no. 12; p. 1101
Main Authors Toyoda, Yasuhiro, Hojo, Shigeyuki, Yoshioka, Setsuko, Noma, Toshiki, Matsunaga, Hiroki, Miyagaki, Hiromichi, Nishida, Hisashi, Shingai, Tatsushi, Takayama, Osamu, Fukuzaki, Takayuki, Ohigashi, Hiroaki, Maeura, Yoshiichi, Tsuji, Motomu
Format Journal Article
LanguageJapanese
Published Japan 01.11.2017
Subjects
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biopsy, Needle
Breast Neoplasms - complications
Breast Neoplasms - drug therapy
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Combined Modality Therapy
Female
Humans
Obesity, Morbid - complications
Treatment Outcome
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Summary:A 39-year-old woman with very sever obesity was admitted to our hospital for a right breast redness and hardness. Her height, weight and BMI were 166 cm, 145 kg and 52.6 kg/m2. Her breast had peau d'orange. CT scan showed swelling of whole right breast and Level I , II lymph node. We performed core needle biopsy and diagnosed as the inflammatory breast cancer with ER and HER2 positive. We introduced chemotherapy(pertuzumab, trastuzumab and paclitaxel)and nutrition counseling in order to reduce her body weight. After 4 courses of chemotherapy, the clinical complete response was obtained and her body weight decreased to 125 kg. We performed mastectomy and axillary node resection and confirmed pathological complete response. Adjuvant chemotherapy(5-FU, epirubicin and cyclophosphamide), adjuvant trastuzumab therapy, postmastectomy radiation therapy and adjuvant hormonal therapy were administered. There have been no signs of recurrence as of 2 years after the operation.
ISSN:0385-0684