Anesthesia and Anti-cancer Therapeutic Agents

An increasing number of cancer patients are treated with anti-cancer chemotherapy and may require not only elective but also emergency surgery. Anti-cancer agents may have adverse effects on various organs and negative effects on subsequent anesthetic management Anesthesiologists must therefore be a...

Full description

Saved in:
Bibliographic Details
Published inMasui. The Japanese journal of anesthesiology Vol. 65; no. 11; p. 1125
Main Authors Ozato, Shojiro, Yokota, Miyuki
Format Journal Article
LanguageJapanese
Published Japan 01.11.2016
Subjects
Anesthetics
Antineoplastic Agents - therapeutic use
Elective Surgical Procedures
Humans
Neoplasms - drug therapy
Online AccessGet more information

Cover

More Information
Summary:An increasing number of cancer patients are treated with anti-cancer chemotherapy and may require not only elective but also emergency surgery. Anti-cancer agents may have adverse effects on various organs and negative effects on subsequent anesthetic management Anesthesiologists must therefore be aware of potential toxicity of anti-cancer agents. The common toxicities include cardiac, pulmonary, bone marrow, renal and hepatic effects. Cardiopulmonary toxicity caused by drugs such as anthracylines and bleomycin is of major concern for anesthesiologists. Other toxicities, however, also require special anesthetic considerations in anes- thesia. Toxicities can be cumulative and irreversible as with anthracyclines, and therefore, attention also has to be paid to the past history of chemotherapy. Preoperative assessment is key to consistent and uncomplicated management of anesthesia. Anesthesi- ologists should take a detailed history of cancer man- agement and understand precise chemotherapy regi- mens and specific side effects experienced by the patient.
ISSN:0021-4892