A retrospective cohort study on the natural history of AIDS caused by blood transfusion

• Published in: Zhōnghuá liúxíngbìng zázhì Vol. 33; no. 7; p. 658
• Main Authors: Chen, Su-Liang, Zhao, Hong-Ru, Zhang, Yu-Qi, Zhao, Cui-Ying, Li, Bao-Jun, Bai, Guang-Yi, Liang, Liang, Chen, Zhi-Qiang, Hui, Yan-Liang, Wang, Wei, Lu, Xin-Li
• Format: Journal Article
• Language: Chinese
• Published: China 01.07.2012
• Subjects: Acquired Immunodeficiency Syndrome - etiology; Antiretroviral Therapy, Highly Active; Blood Donors; Cohort Studies; HIV Infections - epidemiology; HIV Seropositivity; Humans; Incidence; Retrospective Studies; Transfusion Reaction
• ISSN: 0254-6450

To study the natural history of AIDS, caused by blood transfusion. All HIV infections and AIDS patients were from Hebei province, including those infected through blood transfusion around 1995, that were identified as through general census of former commercial plasma donors (FCPDs). Among those objects being observed during the incubation period, 354 had HIV infections (including 142 cases infected via plasmapheresis and 212 cases caused by transfusion) but had not been treated by HAART before the onset of disease. Objects being observed during the survival period, 141 were AIDS patients (including 57 cases infected via plasmapheresis and 84 cases causes by transfusion) but had not been treated by HAART before and after the onset of disease. All infectors and AIDS patients were under follow-up on the progress of illness or death, respectively. By December 31, 2010, the cumulative incidence among HIV infections was 88.70% (314/354), with the incidence density as 9.14/100 person-years (314/3435.75) and the med