Retrospective cohort study on period of incubation and survival among former commercial plasma donors infected with HIV in Hebei province

• Published in: Zhōnghuá yùfáng-yīxué zázhì Vol. 46; no. 4; p. 316
• Main Authors: Chen, Su-liang, Bai, Guang-yi, Li, Qiao-min, Li, Bao-jun, Hui, Yan-liang, Liang, Liang, Wang, Wei, Chen, Zhi-qiang, Lu, Xin-li, Wang, Xiao-feng, Zhang, Yu-qi, Zhao, Hong-ru
• Format: Journal Article
• Language: Chinese
• Published: China 01.04.2012
• Subjects: Adult; Blood Donors; Cohort Studies; Female; HIV - physiology; HIV Infections - epidemiology; HIV Infections - mortality; HIV Infections - virology; Humans; Incidence; Male; Middle Aged; Retrospective Studies; Survival Rate; Virus Latency; Young Adult
• ISSN: 0253-9624

To examine the state of incubation period and survival time of former commercial plasma donors (FCPDs) infected with HIV. All objects infected with HIV were from Hebei province and found from general investigation for FCPDs in 1995. The infector cohort by 142 cases was used to estimate incubation period. In the infector cohort, the time which infectors entered the cohort was their infection time, which was the middle value of the origin date, which was January 1, 1995. The onset of AIDS was defined as an outcome event. End point of observation was Dec 31, 2010. There were 192 months in all from beginning to end. The AIDS cohort by 57 cases was used to estimate the survival of the patients. In the patient cohort, the time of AIDS onset was defined as the time entering the cohort, and death of AIDS was defined as an outcome event. The cumulative incidence ratio, cumulative mortality, illness intensity and mortality intensity were analyzed through Kaplan-Meier. During the observation period, 123 cases of 142 inf