Postoperative cognitive dysfunction in elderly patients after aorta-coronary bypass under conditions of artificial blood circulation.

In patients undergoing open myocardial revascularization under cardiopulmonary bypass (CB), one of the complications is cognitive dysfunction. The aim of the work is to study the effect of intraoperative lactic acidosis, anemia and the duration of myocardial anoxia on the change in cognitive status...

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Bibliographic Details
Published inAdvances in gerontology = Uspekhi gerontologii Vol. 35; no. 6; p. 894
Main Authors Osipova, O A, Shevtsov, R Y, Kukharchuk, A E, Plaksina, K G
Format Journal Article
LanguageRussian
Published Russia (Federation) 2022
Subjects
Acidosis, Lactic - complications
Aged
Aorta
Blood Substitutes
Coronary Artery Bypass - adverse effects
Humans
Postoperative Cognitive Complications
Postoperative Complications - etiology
artificial blood circulation
postoperative cognitive dysfunction
elderly age
coronary bypass surgery
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Summary:In patients undergoing open myocardial revascularization under cardiopulmonary bypass (CB), one of the complications is cognitive dysfunction. The aim of the work is to study the effect of intraoperative lactic acidosis, anemia and the duration of myocardial anoxia on the change in cognitive status with the help of FAB after coronary artery bypass grafting (CABG) with CB. The negative impact of lactic acidosis on cognitive status in patients after CABG has been proven. The relationship between the decrease in hemoglobin concentration during surgery and the negative dynamics of cognitive changes in the postoperative period (R=0,41; p=0,021) was determined. A negative effect of prolonged myocardial anoxia during surgery on the dynamics of cognitive functions of patients was revealed. Thus, the above indicators may be markers of the formation of postoperative cognitive dysfunction in patients undergoing CABG with CB.
ISSN:1561-9125