Phenolic constituents from Lysimachia patungensis

• Published in: Yao hsüeh hsüeh pao Vol. 48; no. 3; p. 377
• Main Authors: Zeng, Peng, Zhang, Yong, Pan, Chen, Jia, Qi, Guo, Fu-Jiang, Zhu, Wei-Liang, Li, Yi-Ming, Chen, Kai-Xian
• Format: Journal Article
• Language: Chinese
• Published: China 01.03.2013
• Subjects: Chalcones - chemistry; Chalcones - isolation & purification; Cinnamates - chemistry; Cinnamates - isolation & purification; Molecular Structure; Phenols - chemistry; Phenols - isolation & purification; Plants, Medicinal - chemistry; Primulaceae - chemistry; Quercetin - analogs & derivatives; Quercetin - chemistry; Quercetin - isolation & purification; Rutin - chemistry; Rutin - isolation & purification
• ISSN: 0513-4870

To study the chemical constituents of Lysimachia patungensis Hand.-Mazz., silica gel column chromatography, reverse phase ODS column chromatography, MCI and Sephadex LH-20, were used to separate the 95% EtOH extract of the whole plant of Lysimachia patungensis Hand.-Mazz.. The structures of the isolated compounds have been established on the basis of chemical and NMR spectroscopic evidence as well as ESI-MS in some cases. Twelve phenolic compounds were obtained and identified as quercetin-3, 3'-di- O-alpha-L-rhamnoside (1), myricetrin (2), quercitrin (3), rutin (4), 2-hydroxynaringenin-4'-O-glucopyranoside (5), naringenin 7-O-glucopyranoside (6), liquiritin apioside (7), licochalcone B (8), tetrahydroxymethoxy chalcone (9), methyl-p-coumarate (10), 2, 4, 6-trihydroxy acetophenone-2-O-glucopyranoside (11) and vaccihein A (12). Among them, compound 1 is a new compound, and compounds 5, 11 and 12 are isolated from the genus Lysimachia L. for the first time, and the others are isolated from the plant for the firs