A New Twist on the Administration of Naldemedine for Opioid-Induced Constipation in an Outpatient

Opioid-induced constipation(OIC)occurs with high frequency in patients with cancer undergoing pain treatment using opioids. Osmotic or irritant laxatives are usually used to prevent OIC. Recently, naldemedine has become operational for OIC. Although naldemedine achieved the desired effect, diarrhea...

Full description

Saved in:
Bibliographic Details
Published inGan to kagaku ryoho Vol. 45; no. 7; p. 1075
Main Authors Shikada, Yasunori, Emi, Yasunori, Kometani, Takuro, Ochiai, Toshiaki, Fujii, Misa, Noda, Yoko, Kajiwara, Mie, Ikeda, Munehiko, Asonuma, Shinichi, Mori, Minami
Format Journal Article
LanguageJapanese
Published Japan 01.07.2018
Online AccessGet more information

Cover

More Information
Summary:Opioid-induced constipation(OIC)occurs with high frequency in patients with cancer undergoing pain treatment using opioids. Osmotic or irritant laxatives are usually used to prevent OIC. Recently, naldemedine has become operational for OIC. Although naldemedine achieved the desired effect, diarrhea is a little feared from the results of clinical phase III study(V9236 clinical trial). We herein report the use of naldemedine to alleviate diarrhea and expect the improvement of the quality of the bowel habits in outpatients with cancer undergoing pain treatment using opioids.
ISSN:0385-0684