Low Plasma High Density Lipoprotein-cholesterol Level Associated with Deep Vein Thrombosis in Traumatic Fracture Patients

To explore the association of plasma high density lipoprotein-cholesterol (HDL-C) and deep vein thrombosis (DVT) in traumatic fracture patients. We performed a retrospective study in 1 054 traumatic fracture patients admitted between April 2012 and December 2014. 188 cases were divided into DVT and...

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Published inSichuan da xue xue bao. Journal of Sichuan University. Yi xue ban Vol. 50; no. 2; p. 248
Main Authors Xu, Bin-Bin, Gou, Ze-Hui, Zhou, Li, Li, Zhi, Chen, Yu, Xue, Xin-Sheng, Li, Hui-Ping
Format Journal Article
LanguageChinese
Published China 01.03.2019
Subjects
Deep vein thrombosis
High density lipoprotein
Fracture
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Summary:To explore the association of plasma high density lipoprotein-cholesterol (HDL-C) and deep vein thrombosis (DVT) in traumatic fracture patients. We performed a retrospective study in 1 054 traumatic fracture patients admitted between April 2012 and December 2014. 188 cases were divided into DVT and others ( =866) into control group based on ultrasound results. The relationship between HDL-C and DVT was determined by univariate and multivariate logistic regression analyses. Compared with control group, patients in DVT group had significantly lower HDL-C level, and low level of plasma HDL-C was associated with the occurrence of DVT. Deceased HDL-C, inceased age, inceased immobilization, inceasd anticoagulant-free days, fracture sites, and blood transfusion were risk factors for the occurrence of DVT in traumatic fracture patients. Patients with surgery had significantly lower level of HDL-C in both groups compared with patients without surgery respectively. Low level of plasma HDL-C was independently associated
ISSN:1672-173X