Surgery treatment and prognosis analysis of 129 small cell carcinoma of the esophagogastric junction

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 43; no. 4; pp. 490 - 496
• Main Authors: Li, B Z, He, M, Chen, X, Zhu, H, Xu, X J
• Format: Journal Article
• Language: Chinese
• Published: China 23.04.2021
• Subjects: Adenocarcinoma - pathology; Carcinoma, Small Cell - surgery; Esophagogastric Junction - pathology; Esophagogastric Junction - surgery; Humans; Lung Neoplasms; Neoplasm Staging; Prognosis; Retrospective Studies; Stomach Neoplasms - drug therapy; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; Esophagogastric junction neoplasms; Survival analysis; Prognosis; Small cell cancer; Surgery
• ISSN: 0253-3766
• DOI: 10.3760/cma.j.cn112152-20200713-00652

To analysis the prognosis related factors of patients with small cell cancer of the esophagogastric junction treated by surgery. The clinicopathologic data of 129 patients with small cell cancer of the esophagogastric junction underwent surgery treatment in the Fourth Hospital of Hebei Medical University from January 2004 to December 2010 were retrospectively analyzed. Univariate survival survival was performed by Kaplan-Meier method and Log rank test. Multivariate survival was analyzed by using Cox proportional hazard model. Radical surgery was performed in 123 patients, whereas other 6 cases were conducted palliative operation. The 5-year overall survival (OS) rate of this cohort was 21.0% and median survival time was 25.7 months. The 5-year progression free survival (PFS) rate of this cohort was 11.0% and median PFS time was 19.1 months. The univariate analysis result showed that operation manner, radical or not, tumor length, lymph node metastasis, TNM stage, intravascular cancer embolus surgical margin p