Disease burden of acute viral hepatitis in Guangdong Province, 1990-2019

• Published in: Zhōnghuá liúxíngbìng zázhì Vol. 45; no. 3; p. 365
• Main Authors: Qiu, J M, Zeng, F F, Cheng, C, Wen, H Y, Huang, S Q, Liu, D, Qi, J L, Yin, P, Zhou, M G, Xu, Y, Liu, Z P, Mei, Q S, Xiao, H, Xiang, Z, Liang, X F
• Format: Journal Article
• Language: Chinese
• Published: China 10.03.2024
• Subjects: Adult; Aged; Child; China - epidemiology; Cost of Illness; Female; Global Burden of Disease; Hepatitis A - epidemiology; Hepatitis B - epidemiology; Humans; Incidence; Male; Quality-Adjusted Life Years; China
• ISSN: 0254-6450
• DOI: 10.3760/cma.j.cn112338-20230830-00108

To examine the burden and trends of acute viral hepatitis in Guangdong Province from 1990 to 2019, and provide reference evidences for hepatitis prevention and control in the province. Data on acute viral hepatitis (hepatitis A, B, C, and E) in Guangdong from 1990 to 2019 were extracted from the Global Burden of Disease Study 2019 database. The incidence, prevalence, mortality, and disability-adjusted life years (DALY) data were analyzed by age and gender, and the estimated annual percentage change (EAPC) was calculated to describe the changing trends in disease burden. From 1999 to 2019, the standardized incidence, prevalence, mortality, and DALY of acute viral hepatitis in Guangdong were higher than the national averages. In 2019, 51.43% (2 245 087/4 365 221) of acute viral hepatitis cases in Guangdong Province were mainly attributed to hepatitis B, and 77.18% (106/138) of deaths were due to acute hepatitis B. In different age groups, except for acute hepatitis B, which was more common in adults, the incide