Seroepidemiological survey of Toxoplasma gondii infection in patients with gynecological malignant tumors

• Published in: Zhongguo xue xi chong bing fang zhi za zhi Vol. 30; no. 6; p. 682
• Main Authors: Xi-Ming, Qian, Guo-Qiang, Shen, Xiao-Ming, Wang
• Format: Journal Article
• Language: Chinese
• Published: China 19.02.2019
• Subjects: Toxoplasma gondii; Seroepidemiological survey; Gynecological malignant tumor
• ISSN: 1005-6661
• DOI: 10.16250/j.32.1374.2019036

To investigate the seroprevalence of infection in patients with gynecological malignant tumors, so as to provide the evidence for the control of infections in the patients with gynecological malignant tumors. A total of 327 patients with gynecological malignant tumors were recruited, and 200 women with normal healthy examinations were served as controls. The serum anti- IgG and IgM antibodies were detected by using ELISA, and the seroprevalence was compared between the patients and controls, and among various types of cancers. The overall seroprevalence of was 26.91% (88/327) in the patients with gynecological malignant tumors, which was significantly higher than that (5.00%) in the healthy volunteers ( = 39.36, <0.01) . The prevalence of anti- IgG antibody in the cancer patients was significantly higher than that in the controls (26.30% vs. 5.00%; = 37.79, <0.01), while the prevalence of anti- IgM antibody in the cancer patients was not significantly different from that in the controls (0.92% . 0; corrected