The effect of autologous mesenchymal stem cells of bone marrow origin on regeneration of damaged rat bottom jaw bone

The regeneration processes after introduction in site of damaged bone of rat bottom jaw of autologous mesenchymal stem cells of bone marrow origin (AMSCBMO) in suspension were studied by methods of light microscopy and x-ray densitometry. Morphological methods showed that formation of red bone marro...

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Bibliographic Details
Published inStomatologija (Moskva) Vol. 91; no. 1; p. 5
Main Authors Maĭborodin, I V, Matveeva, V A, Kolesnikov, I S, Drovosekov, M N, Toder, M S, Shevela, A I
Format Journal Article
LanguageRussian
Published Russia (Federation) 2012
Subjects
Animals
Bone Marrow - physiology
Bone Regeneration
Male
Mandible - cytology
Mandible - diagnostic imaging
Mandible - physiology
Mandible - surgery
Mandibular Injuries - surgery
Mesenchymal Stem Cell Transplantation
Mesenchymal Stromal Cells - cytology
Mesenchymal Stromal Cells - physiology
Osteogenesis
Radiography
Rats
Rats, Inbred Strains
Transplantation, Autologous
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Summary:The regeneration processes after introduction in site of damaged bone of rat bottom jaw of autologous mesenchymal stem cells of bone marrow origin (AMSCBMO) in suspension were studied by methods of light microscopy and x-ray densitometry. Morphological methods showed that formation of red bone marrow in bone callosity occurs much earlier after use AMSCBMO than in the time of natural course of reparation. Formation of cavities with a marrow decreases tissue density after application AMSCBMO in a site of damage in 4 and 5 weeks of supervision. The specified changes progress during all time of observation and are the certificate of accelerated development of regenerative processes in bone tissue.
ISSN:0039-1735