A Case of Curative Resection of Locally Advanced Gastric Cancer after Nutrition Therapy and Chemotherapy with S-1 and Oxaliplatin Using Elemental Diet Tube

We report a case of advanced gastric cancer with stenosis under severe malnutrition, in which nutritional treatment along with chemotherapy using an elemental diet(ED)tube led to complete resection of the tumor. A 66-year-old man who presented with difficulty in dietary intake came to our hospital....

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 46; no. 13; p. 2422
Main Authors Deguchi, Sota, Tendo, Masashige, Tani, Naoki, Sakimura, Chie, Masuda, Go, Hori, Takeshi, Nakata, Bunzo, Ishikawa, Tetsuro, Hirakawa, Kosei
Format Journal Article
LanguageJapanese
Published Japan 01.12.2019
Subjects
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Drug Combinations
Food, Formulated
Gastrectomy
Humans
Male
Neoadjuvant Therapy
Neoplasm Recurrence, Local
Nutrition Therapy
Oxaliplatin
Oxonic Acid
Stomach Neoplasms - therapy
Tegafur
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Summary:We report a case of advanced gastric cancer with stenosis under severe malnutrition, in which nutritional treatment along with chemotherapy using an elemental diet(ED)tube led to complete resection of the tumor. A 66-year-old man who presented with difficulty in dietary intake came to our hospital. He was emaciated with a body mass index(BMI)score of 13.5 and a prognostic nutritional index(PNI)score of 33.8 and was admitted to the hospital for an emergency. He was diagnosed with advanced gastric cardia cancer invading the distal pancreas, spleen, and left diaphragm(U, type 3, tub2, cT4bN3M0, cStage ⅢC, HER2 score 0). There was obstruction of the passage of food due to the tumor, we performed nutrition therapy and chemotherapy consisting of 3 courses of S-1 and oxaliplatin using an ED tube. After chemotherapy, the primary tumor and lymph nodes were reduced, and we performed total gastrectomy with D2 lymph node, distal pancreas, spleen, and left partial diaphragm dissection. Histopathological diagnosis was ypT4aN1M0, ypStage ⅢA, indicating a pathological partial response(Grade 1). Adjuvant chemotherapy was performed for 6 months, and there has been no relapse for 3 years since the operation.
ISSN:0385-0684