Sarcomatoid Squamous Cell Carcinoma Of The Vulva:A Case Report

• Published in: Clinica terapeutica Vol. 172; no. 5; p. 392
• Main Authors: Iavazzo, C, Karavioti, E, Kokkali, K, Souka, E, Psomiadou, V, Lekka, S, Geramani, E, Fotiou, A, Vorgias, G
• Format: Journal Article
• Language: English
• Published: Italy 29.09.2021
• Subjects: Aged; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - surgery; Female; Humans; Lymphatic Metastasis; Neoplasm Recurrence, Local; Vulvar Neoplasms - diagnosis; Vulvar Neoplasms - surgery; carcinosarcoma; Vulvar cancer; Squamous cell carcinoma; Sarcoma; spindle cell carcinoma
• ISSN: 1972-6007
• DOI: 10.7417/CT.2021.2345

A sarcomatoid squamous cell carcinoma of the vul-va is a very rare malignancy of the female genital tract . It has been characterized as an aggressive disease typically associated with early development of local recurrences as well as distant metastases. A 77-year old woman presented to our hospital with an aggravated vulvar mass, complaining about pruritus and pain. The patient underwent a radical vulvectomy with bilateral inguinal lymph node dissection and bilateral pelvic lymph node sampling. The histo-pathologic examination was consistent with a sarcomatoid squamous cell carcinoma of the vulva with an identical microscopic and im-munohistochemical appearance. The FIGO stage was IB and further management was decided to be radiotherapy. A sarcomatoid squamous cell carcinoma is a rare entity with an aggressive biological behavior. To date, there have been only a few cases of the disease reported in the literature. Therefore a more systematic collection and closer study of such cases would be helpful for achieving an early diagnosis and more effective therapeutic strategies in the future.