Research progress on induced membrane technique for the treatment of segmental bone defect

Treatment of large bone defects caused by trauma, osteomyelitis, and tumors has been a major challenge in clinical. In the past, there have been many ways to repair and reconstruct the large bone defects. However, there is a long period of treatment, high technical requirement and complications such...

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Bibliographic Details
Published inZhongguo gu shang Vol. 31; no. 5; p. 488
Main Authors Jin, Zhi-Chao, Cai, Qun-Bin, Zeng, Zhi-Kui, Li, Ding, Li, Yue, Huang, Pei-Zhen, Zheng, Xiao-Hui
Format Journal Article
LanguageChinese
Published China 25.05.2018
Subjects
Bone Diseases - surgery
Bone Transplantation
Fracture Fixation, Internal
Humans
Retrospective Studies
Vascular Endothelial Growth Factor A
Review literature
Bone defect
Induced membrane
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Summary:Treatment of large bone defects caused by trauma, osteomyelitis, and tumors has been a major challenge in clinical. In the past, there have been many ways to repair and reconstruct the large bone defects. However, there is a long period of treatment, high technical requirement and complications such as ununion. After Masquelet reported the induced membrane technology in 2000, the technique was widely used in treatment of trauma, osteomyelitis, and large bone defects caused by tumors. It has been obtained good results. It has the advantages of short course, high healing rate, easy operation and easy to master. The induced membrane has unique structural characteristics and biological characteristics. There are many kinds of osteogenic factors that are included in the membrane, such as vascular endothelial growth factor, and morphogenetic protein-2, transforming growth factor-β1, etc. These osteogenic factors contribute to accelerate bone healing. With the development of induced membrane technology. The technolo
ISSN:1003-0034
DOI:10.3969/j.issn.1003-0034.2018.05.018