Teratozoospermia and karyopathological abnormalities in epithelial urogenital tract cells in male shift workers with varicocele in oil fields of the north of Siberia

• Published in: Urologii͡a︡ (Moscow, Russia : 1999) no. 4; p. 82
• Main Authors: Ilyinskikh, N N, Ilyinskikh, E N, Saushkin, S A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.08.2016
• Subjects: Adult; Chromosome Aberrations; Humans; Male; Occupational Diseases - complications; Occupational Diseases - pathology; Oil and Gas Fields; Oil and Gas Industry; Teratozoospermia - complications; Teratozoospermia - pathology; Urothelium - ultrastructure; Varicocele - complications; Varicocele - pathology; Young Adult; karyopathology; teratozoospermia; oil field workers; varicocele
• ISSN: 1728-2985

The aim of this work was to study associations between varicocele and the various types of karyopathologic abnormalities in epithelial urogenital tract cells or teratozoospermia in oil field shift workers of the north of Siberia. We examined 139 male individuals in several oil field of the north of Tomsk and Tyumen regions. The examined individuals were divided in 4 groups: 1) driller-workers with varicocele; 2) driller-workers without varicocele; 3) oil field administrative staff with varicocele, and 4) oil field administrative staff without varicocele. Samples of both the sperm ejaculate and the epithelial urogenital tract cells were obtained from all the individuals for microscopic assay. It was found that the frequencies of both the teratozoospermia and the various karyopathologic abnormalities in epithelial urogenital cells were significantly higher in the workers with varicocele compared to all the other groups. There were correlations between karyopathologic abnormalities in epithelial urogenital cells and teratozoospermia in both the driller-workers with varicocele and the oil field administrative staff with varicocele. However, the frequencies of damaged cells in this workers group were significantly higher than the ones in the administrative staff with varicocele, which can be associated with the genotoxic effects of work conditions at oil fields of the north of Siberia. From the data it was concluded that the increased frequencies of the abnormalities in the epithelial urogenital cells and the sperm in the driller-workers with varicocele may be associated with both the diseases endogenous factor and the genotoxic effects of work conditions at the oil fields.