Spatial distribution pattern of local tumor progression analysis after microwave ablation of hepatocellular carcinoma based on three-dimensional magnetic resonance imaging

• Published in: Zhonghua gan zang bing za zhi Vol. 32; no. 3; p. 208
• Main Authors: Fan, F Y, Ding, W Z, Liu, F Y, Cheng, Z G, Han, Z Y, Yu, X L, Liang, P, Yu, J
• Format: Journal Article
• Language: Chinese
• Published: China 20.03.2024
• Subjects: Carcinoma, Hepatocellular - pathology; Catheter Ablation - methods; Humans; Imaging, Three-Dimensional - methods; Liver Neoplasms - pathology; Magnetic Resonance Imaging - methods; Microwaves - therapeutic use; Retrospective Studies; Treatment Outcome; Thermal ablation; Recurrence; Spatial distribution characteristics; Hepatocellular carcinoma
• ISSN: 1007-3418
• DOI: 10.3760/cma.j.cn501113-20231123-00219

To investigate the spatial distribution pattern of local tumor progression (LTP) for hepatocellular carcinoma (HCC) ≤5 cm after microwave ablation. A retrospective analysis was performed on 169 HCCs with matched MRI before and after ablation from December 2009 to December 2019. A tumor MRI was reconstructed using three-dimensional visualization technology. LTP was classified as contact or non-contact, early or late stage, according to whether LTP was in contact with the edge of the ablation zone and the occurrence time (24 months). The tumor-surrounded area was divided into eight quadrants by using the eight-quadrant map method. An analysis was conducted on the spatial correlation between the quadrant where the ablative margin (AM) safety boundary was located and the quadrant where different types of LTP occurred. The t-test, or rank-sum test, was used for the measurement data. 2-test for count data was used to compare the difference between the two groups. The AM quadrant had a distribution of 54.4% LTP, 64.