Lung function measurements using body plethysmography in young children with acute lower respiratory tract infection

• Published in: Zhonghua er ke za zhi Vol. 52; no. 7; p. 525
• Main Authors: Zhang, Xiaobo, Jiang, Gaoli, Wang, Libo, Liu, Lijuan, Shi, Peng, Wan, Chengzhou, Qian, Liling
• Format: Journal Article
• Language: Chinese
• Published: China 01.07.2014
• Subjects: Airway Resistance - physiology; Case-Control Studies; Child, Preschool; Female; Functional Residual Capacity - physiology; Humans; Infant; Lung - physiopathology; Male; Plethysmography, Whole Body; Respiratory Function Tests; Respiratory Sounds - diagnosis; Respiratory Sounds - physiopathology; Respiratory Tract Diseases - diagnosis; Respiratory Tract Diseases - physiopathology; Tidal Volume
• ISSN: 0578-1310

Body plethysmography is a typical method to measure functional residual capacity (FRC) and airway resistance (Raw). The aim of the study was to test the feasibility of measuring lung function with the body plethysmography in young children with acute lower respiratory tract infection (ALRI) by evaluating changes and prognosis of lung function for infants with ALRI with or without wheezing via body plethysmograph. Pulmonary function tests (PFTs) were performed by using body plethysmography in 444 children with ALRI, aged 1-36 months, to assess their tidal breathing parameters such as ratio of time to peak tidal expiratory flow to total expiratory time (TPTEF/TE), ratio of volume to peak tidal expiratory flow to total expiratory volume (VPTEF/VE), plethysmographic functional residual capacity (FRCP), FRCP per kilogram (FRCP/kg), specific effective airway resistance (sReff), effective airway resistance (Reff), Reff per kilogram (Reff/kg), etc. According to whether there was wheezing or not, children who had ALRI