Association of Insulin Resistance and β Cell Function with Lipid Metabolism in Middle-aged and Elderly Hui and Han Populations

• Published in: Zhōngguó yīxué kēxuéyuàn xuébào Vol. 38; no. 2; p. 192
• Main Authors: Li, Shu-ya, Jiang, Min, Yao, Tian-yu, Cheng, Yu-xuan, Fan, Ya-jie, Liu, Xu-ying, Zhang, Jin-ling, Liu, Lan, Wang, Zhi-zhong, Ma, Yu-ying, Hu, Xue-qin, Wang, Pan-pan, Yu, Jing-jing, Ma, Rong, Huang, Qi
• Format: Journal Article
• Language: Chinese
• Published: China 01.04.2016
• Subjects: Aged; Asian Continental Ancestry Group; Blood Glucose - analysis; Body Mass Index; Cholesterol - blood; Ethnic Groups; Humans; Insulin - blood; Insulin Resistance; Insulin-Secreting Cells - cytology; Lipid Metabolism; Middle Aged; Triglycerides - blood; Uric Acid - blood
• ISSN: 1000-503X
• DOI: 10.3881/j.issn.1000-503X.2016.02.012

To explore the association of insulin resistance and β cell function with lipid metabolism in middle-aged and elderly Hui and Han populations. A total of 1000 subjects age over 40 years were recruited from five urban communities in Yinchuan and Wuzhong cities of Ningxia. The composition ratio between Hui and Han nationality was 1:2. A questionnaire-based survey was performed. Physical examinations were carried out to measure the height, body mass, waistline, and hipline. The levels of triglyceride (TG), total cholesterol (TC), blood uric acid (BUA), fasting blood glucose and insulin were measured. The boby mass index (BMI), waist-hip ratio (WHR), and secretion related index including insulin resistance index (IR), insulin sensitivity index (IAI), and beta cell function index (HBCI) were calculated. The BMI, WHR, IAI, HBCI, and the prevalence rate of diabetes in Hui nationality were significantly higher than those in Han nationality (P<0.01). The levels of BUA, fasting blood glucose, TC, and IR in Han national