Urticaria Pigmentosa Without Pruritus

Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To our knowledge, we are describing the first...

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Published inJournal of drugs in dermatology Vol. 23; no. 3; p. e81
Main Authors Nahm, William J, Corriveau, Denise J, Mathe, Chris A, Wyant, W Austin, Vega, Carlos, Arthur, Anita, Min, K Chris
Format Journal Article
LanguageEnglish
Published United States 01.03.2024
Subjects
Emotions
Humans
Mast Cells
Pruritus - diagnosis
Pruritus - etiology
Urticaria - diagnosis
Urticaria Pigmentosa - diagnosis
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Summary:Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To our knowledge, we are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier's sign, stated that they never felt itchy, and denied ever using a topical steroid or antihistamine. Although our patient declined additional testing, patients like this may benefit from a detailed evaluation of their sensory system through both quantitative sensory testing and genetic analysis. J Drugs Dermatol. 2024;23(3): doi:10.36849/JDD.7558e.
ISSN:1545-9616
DOI:10.36849/jdd.7558