Effect of Dichloromethane Extraction Phase of Patrinia Scabiosaefolia Fisch. Stem on Proliferation and Differentiation of K562 Cells

• Published in: Zhongguo shi yan xue ye xue za zhi Vol. 31; no. 1; p. 25
• Main Authors: Mi, Le-Yuan, Li, Ke-Jing, Li, Shan, Liu, Ting, Chai, Xiao-Jing, Zhang, Ying, Li, Juan
• Format: Journal Article
• Language: Chinese
• Published: China 01.02.2023
• Subjects: Apoptosis; Cell Differentiation; Cell Proliferation; Humans; K562 Cells; Methylene Chloride - pharmacology; Patrinia; cell apoptosis; induced differentiation; K562 cell line; Patrinia scabiosaefolia Fisch. Stem; dichloromethane extraction phase

To explore the effect of dichloromethane extraction phase of ethanol extract from stem of Patrinia scabiosaefolia Fisch.(DPSS) on proliferation and differentiation of K562 cells and its related mechanism. MTT assay was used to detect the effects of DPSS at 0, 25, 50, 100 and 200 μg/ml on the prolife...