Joint association of depression symptoms and 10-year risk of ischemic cardiovascular disease with the cardiovascular disease in middle-aged and elderly people in China

• Published in: Beijing da xue xue bao. Journal of Peking University. Yi xue ban Vol. 55; no. 3; p. 465
• Main Authors: Zhang, Z W, Hua, Y M, Liu, A P
• Format: Journal Article
• Language: Chinese
• Published: China 18.06.2023
• Subjects: Aged; Cardiovascular Diseases - epidemiology; China - epidemiology; Depression - complications; Depression - epidemiology; Humans; Longitudinal Studies; Middle Aged; Risk Factors; China; Cardiovascular disease; Depressive symptoms; Joint association; Ischemic cardiovascular disease
• ISSN: 1671-167X
• DOI: 10.19723/j.issn.1671-167X.2023.03.012

To explore joint association of depression symptoms and 10-year risk of ischemic cardiovascular disease (CVD) in middle-aged and elderly people in China. Based on China Health and Retirement Longitudinal Study(CHARLS)database using 2011 baseline data and the follow-up cohort data of 2013, 2015 and 2018, describe the distribution characteristics of baseline depressive symptoms and 10-year risk of ischemic cardiovascular disease in 2011. Cox survival analysis model was used to analyze the individual, independent and joint association of depression symptoms and 10-year risk of ischemic cardiovascular disease with cardiovascular disease. A total of 9 412 subjects were enrolled. The detection rate of depressive symptoms at baseline was 44.7%, and the 10-year middle and high risk of ischemic cardiovascular disease was 13.62%. During an average follow-up of 6.19 (6.19±1.66) years, 1 401 cases of cardiovascular disease were diagnosed in 58 258 person-years, revealing an overall incidence density of 24.048/1 000 perso