Study of blood flow improvement of topical application of estrogen on low genitourinary tract and its safety

• Published in: Zhong hua yi xue za zhi Vol. 92; no. 39; p. 2778
• Main Authors: Huang, Feng-hua, Zhang, Xiao-li, Xiao, Li-ping, Xu, Yi-yong, Zhang, Yuan-zhen
• Format: Journal Article
• Language: Chinese
• Published: China 23.10.2012
• Subjects: Adult; Estrogens - administration & dosage; Female; Hemodynamics; Humans; Middle Aged; Ultrasonography, Doppler, Color; Urethra - blood supply; Urethra - diagnostic imaging; Urinary Bladder - blood supply; Urinary Bladder - diagnostic imaging; Vagina - blood supply; Vagina - diagnostic imaging
• ISSN: 0376-2491
• DOI: 10.3760/cma.j.issn.0376-2491.2012.39.012

The study of blood flow improvement of local estrogen on the low genitourinary tract and its safety. The color Doppler flow imaging technique was employed to observe the flow spectrum of genitourinary tract. During the period of February 2007 to December 2010, there were 78 cases of postmenopausal females on local estrogen. The Doppler parameters included vaginal wall, urethra resistance index (RI) and systolic/diastolic ratio and others. And the lower genital urinary tract symptoms, such as sexual satisfaction, vulvovaginitis, urinary frequency, nocturia and other improvements, as well as adverse drug reactions before treatment and after 1 month, 3 months were recorded and analyzed. The results before treatment and after 1 month, 3 months, vaginal wall artery RI were 0.9 ± 0.2, 0.6 ± 0.2 and 0.7 ± 0.3; S/D 8.6 ± 3.7, 6.0 ± 2.9 and 6.4 ± 2.1; urethral artery RI 0.7 ± 0.2, 0.6 ± 0.2 and 0.6 ± 0.2, S/D 6.6 ± 1.9, 3.5 ± 0.7 and 3.4 ± 0.5 respectively. When the pre- and post-treatment indices were compared, the d