Evaluation of the quality of life (Whoqol-Bref) among methadone and suboxone substitution state program patients and healthy volunteers in Georgia

to evaluate QOL patients being treated with methadone and Suboxone in State-sponsored programs in Georgia. The WHOQOL-BREF (26 questions) version was administered to patients in State substitution program and healthy volunteers to assess their overall function and life satisfaction in physical, ment...

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Bibliographic Details
Published inGeorgian medical news no. 213; p. 44
Main Authors Piralishvili, G, Gamkrelidze, I, Nikolaishvili, N, Chavchanidze, M
Format Journal Article
LanguageEnglish
Published Georgia (Republic) 01.12.2012
Subjects
Adult
Aged
Buprenorphine - therapeutic use
Buprenorphine, Naloxone Drug Combination
Case-Control Studies
Female
Georgia (Republic)
Government Programs
Humans
Male
Methadone - therapeutic use
Middle Aged
Naloxone - therapeutic use
Opiate Substitution Treatment - methods
Opiate Substitution Treatment - psychology
Quality of Life
Social Change
Surveys and Questionnaires
Young Adult
Georgia (Republic)
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Summary:to evaluate QOL patients being treated with methadone and Suboxone in State-sponsored programs in Georgia. The WHOQOL-BREF (26 questions) version was administered to patients in State substitution program and healthy volunteers to assess their overall function and life satisfaction in physical, mental, social health, and environment domains. Domain scores were calculated and converted to 4-20 and 0-100 scales, identical to the WHOQOL-100. 485 patients (309 from 6 Tbilisi and 176 from 5 regional centers) and 50 healthy volunteers (13 male, 37 female) were surveyed. Significant differences were observed between new admitted patients (0-3 month) and healthy controls by mean physical (47.5 vs. 51.94; CI 95%); psychological (55.0 vs. 60.50; CI 95%) and environmental (46.2 vs. 52.2; CI 95%) domains, but not by social relationships or between Tbilisi and regions. The Social domain scores were raised in accordance with time spent in treatment reaching a maximum improvement within 1-3 years (social- 72.8 vs. 67.7; CI 95%), further with few descending tends round the healthy people's scores. These pilot data show decrements in QOL among patients entering maintenance treatment with improvements in the course of maintenance treatment. It is possible that the increased indicators in social domain up to especially high level within the first 3 years is the result of subjective factors, with the subsequent return to healthy community level.
ISSN:1512-0112