Association between long-term exposure to ambient ozone and sperm quality in Shandong Province

• Published in: Zhōnghuá yùfáng-yīxué zázhì Vol. 58; no. 5; p. 592
• Main Authors: Qu, Y N, Han, W K, Song, X H, Zhao, Q, Ma, W, Wang, L
• Format: Journal Article
• Language: Chinese
• Published: China 06.05.2024
• Subjects: Adult; Air Pollutants - analysis; China; Environmental Exposure - adverse effects; Humans; Male; Ozone - adverse effects; Ozone - analysis; Semen Analysis; Sperm Count; Sperm Motility - drug effects; Spermatozoa - drug effects; China
• ISSN: 0253-9624
• DOI: 10.3760/cma.j.cn112150-20230818-00105

To evaluate the association between long-term exposure to ambient ozone (O ) and sperm quality. From January 1, 2014, to December 31, 2019, healthy sperm donors were recruited through the Human Sperm Bank of Shandong University Affiliated Reproductive Hospital. A total of 37 977 sperm donation data from 2 971 healthy volunteers were analyzed. The average annual O concentration (0.01°× 0.01°) was matched according to household address. A multivariate mixed-effect model was used to analyze the exposure-response relationship between the average O exposure concentration and sperm quality in the previous year, with each donor as a random intercept. All results were presented as % changes with 95% confidence intervals ( ) for all sperm parameters associated with 10 μg/m increases in O . The effects of individual characteristics on the association between O and sperm quality were evaluated by stratified analysis. The average O concentration in the year before semen collection was (107.09±7.50) μg/m . Each 10 μg/m in