A head-to-head comparison of contemporary indolent prostate cancer screen protocols in Chinese

• Published in: Beijing da xue xue bao. Journal of Peking University. Yi xue ban Vol. 47; no. 4; p. 586
• Main Authors: Fan, Yu, Liu, Zhuo, Zhang, Lian, Li, De-run, He, Qun, Yang, Xin-yu, Shen, Qi, Hu, Shuai, Liu, Li-bo, Shan, Gang-zhi, Li, Shu-qing, Meng, Yi-sen, Wang, Yu, Yu, Wei, Zhang, Qian, He, Zhi-song, Zhou, Li-qun, Jin, Jie
• Format: Journal Article
• Language: Chinese
• Published: China 18.08.2015
• Subjects: Asian Continental Ancestry Group; Biopsy; Early Detection of Cancer - methods; Humans; Male; Neoplasm Grading; Prostatectomy; Prostatic Neoplasms - diagnosis; Retrospective Studies
• ISSN: 1671-167X

To compare the diagnostic accuracy of five internationally used indolent prostate cancer screen protocols in Chinese prostate cancer patients. Retrospective analysis was made of the consecutive cohort of 314 patients, from Jan. 2006 to Apr. 2014, who had both prostate biopsy and radical prostatectomy in Peking University First Hospital. The Gleason score≤6, pT2, tumor volume≤0.5 mL, margin negative and lymph nodes negative were defined as indolent prostate cancer. The predictive value of five indolent screen criteria including Epstein, Memorial Sloan-Kettering Cancer Center (MSKCC), Prostate Cancer Research International: Active Surveillance (PRIAS), University of California, San Francisco (UCSF), and University of Miami (UM) were evaluated in Chinese prostate cancer patients. Measures of diagnostic accuracy and areas under the receiver-operating curve (AUC) were calculated for each protocol and compared. A total of 16% (49 cases) of the patients met the inclusion criteria of at least one protocol, including