Association of blood oxidative stress level with hypertriglyceridemia in the elderly aged 65 years and older in 9 longevity areas of China

• Published in: Zhōnghuá yùfáng-yīxué zázhì Vol. 55; no. 1; p. 18
• Main Authors: Tan, Q Y, Lyu, Y B, Zhou, J H, Zhang, M Y, Chen, C, Zhao, F, Li, C C, Qu, Y L, Ji, S S, Lu, F, Liu, Y C, Gu, H, Wu, B, Cao, Z J, Zhao, S H, Shi, X M
• Format: Journal Article
• Language: Chinese
• Published: China 06.01.2021
• Subjects: Aged; Aged, 80 and over; China; Cohort Studies; Humans; Hypertriglyceridemia; Longevity; Male; Oxidative Stress; China; Aged; Cross-sectional studies; Hypertriglyceridemia; Blood oxidative stress level
• ISSN: 0253-9624
• DOI: 10.3760/cma.j.cn112150-20200728-01065

To investigate the association of blood oxidative stress level with hypertriglyceridemia in the elderly aged 65 years and older in China. A total of 2 393 participants aged 65 years and older were recruited in 9 longevity areas from Heathy Aging and Biomarkers Cohort Study, during 2017 to 2018. Information on demographics characteristic, life style and health status were collected by questionnaire and physical examination, and venous blood was collected to detect the levels of blood oxidative stress and hypertriglyceridemia. The linear or non-linear association between oxidative stress and hypertriglyceridemia was described by restrictive cubic splines (RCS) fitting multiple linear regression model. The generalized linear mixed effect model was conducted to assess the association between oxidative stress and hypertriglyceridemia. A total of 2 393 participants, mean age was 84.6 years, the youngest was 65 and the oldest was 112, the male was 47.9%(1 145/2 393), the triglyceride level was (1.4±0.8) mmol/L. The