Effects of bisphenol A on the female reproductive organs and their mechanisms

Bisphenol A (BPA) is a commonly used phenolic environmental estrogen. Long-term exposure of female mammalians to BPA can lead to endocrine disorders, followed by the morphological and functional changes in ovary, uterus, vagina, and oviducts. The interactions of BPA with various target molecules or...

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Published inZhōngguó yīxué kēxuéyuàn xuébào Vol. 35; no. 6; p. 683
Main Authors Yan, Pei-pei, Pan, Xiao-yan, Wang, Xue-nan, Wang, Zheng-chao, Li, Zhi-xin, Wan, Ying, He, Zhi, Dou, Zhao-hua
Format Journal Article
LanguageChinese
Published China 01.12.2013
Subjects
Benzhydryl Compounds - toxicity
Endocrine Disruptors - toxicity
Estrogens, Non-Steroidal - toxicity
Female
Humans
Ovary - drug effects
Phenols - toxicity
Uterus - drug effects
Vagina - drug effects
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Summary:Bisphenol A (BPA) is a commonly used phenolic environmental estrogen. Long-term exposure of female mammalians to BPA can lead to endocrine disorders, followed by the morphological and functional changes in ovary, uterus, vagina, and oviducts. The interactions of BPA with various target molecules or tissues will cause different effects. To further elucidate the effects of BPA on female reproductive system, we review the changes in the structure and functions of female reproduction system after BPA exposure and their possible mechanisms.
ISSN:1000-503X
DOI:10.3881/j.issn.1000-503X.2013.06.018