Clinicopathological and survival features of primary hepatic lymphoma: an analysis of 35 cases

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 35; no. 9; p. 689
• Main Authors: Zhao, Qian, Liu, Hai-ping, Gu, Yi-jin, Cong, Wen-ming
• Format: Journal Article
• Language: Chinese
• Published: China 01.09.2013
• Subjects: Adolescent; Adult; Aged; alpha-Fetoproteins - metabolism; Antigens, CD20 - metabolism; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - therapy; Carcinoma, Hepatocellular - virology; Chemotherapy, Adjuvant; Cyclophosphamide - therapeutic use; Doxorubicin - therapeutic use; Female; Follow-Up Studies; Hepatitis B - complications; Hepatitis B Surface Antigens - metabolism; Hepatitis C Antibodies - metabolism; Humans; Leukocyte Common Antigens - metabolism; Liver Cirrhosis - complications; Liver Neoplasms - pathology; Liver Neoplasms - therapy; Liver Neoplasms - virology; Lymphoma - pathology; Lymphoma - therapy; Lymphoma - virology; Lymphoma, B-Cell, Marginal Zone - pathology; Lymphoma, B-Cell, Marginal Zone - therapy; Lymphoma, B-Cell, Marginal Zone - virology; Lymphoma, Large B-Cell, Diffuse - pathology; Lymphoma, Large B-Cell, Diffuse - therapy; Lymphoma, Large B-Cell, Diffuse - virology; Lymphoma, T-Cell - pathology; Lymphoma, T-Cell - therapy; Lymphoma, T-Cell - virology; Male; Middle Aged; Prednisone - therapeutic use; Retrospective Studies; Survival Rate; Vincristine - therapeutic use; Young Adult
• ISSN: 0253-3766

To evaluate the clinicopathological features and prognosis of primary hepatic lymphoma (PHL). Thirty-five patients with PHL who underwent surgical resection and were confirmed by pathology in our hospital from 1982 to 2012 were re-evaluated for clinicopathological data, including their symptoms, radiological features, recurrence interval, histopathological properties and prognosis. Of the 35 patients, 25 were men (71.4%) and 10 were women (28.6%), with an average age of 52.6 years old (range, 17-79 years). Presented symptoms were epigastric phymatosis, abdominal pain and low-grade fever. In the present study, 21 (60.0%) patients were positive for HBsAg, 1(2.9%) patient was positive for anti-HCV, 3 patients were positive for AFP, 12 patients and 2 patients were complicated by cirrhosis and hepatocellular carcinoma, respectively. Pathologically, 35 PHL were classified into 19 DLBCL (54.3%), 13 T cell-lymphoma (37.1%), and 3 MALT lymphoma (8.6%). Patients with DCBCL showed better postoperative survival than pati