Hypoxemia induced the changing structure of the lung tissue in SD rat though changing blood clotting and the effects of breviscapine's intervention

• Published in: Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban Vol. 45; no. 4; p. 567
• Main Authors: Huang, Jian-Ge, Xie, Min, Zhang, Xu, He, Qiu-Ying, He, Gao-Yan
• Format: Journal Article
• Language: Chinese
• Published: China 01.07.2014
• Subjects: Animals; Blood Coagulation; Bronchoalveolar Lavage Fluid; Flavonoids - pharmacology; Hypoxia - pathology; Lung - pathology; Plasminogen Activator Inhibitor 1 - metabolism; Protein C - metabolism; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1 - metabolism

To investigate the expressions of plasminogen activator inhibitor-1 (PAI-1), activated protein C (APC) and the histology structures of the rat lung tissues in the different hypoxia time; and to investigate the effects of breviscapine to the above changes. Eighty SD rats were randomly divided into A...