The association between body mass index and non-alcoholic fatty liver disease

To investigate the association of body mass index (BMI) with alcoholic fatty liver disease (NAFLD). A cohort of 725 adult subjects underwent general health check-up at our hospital in July 2008, then were followed up in 2011. The clinical data including body mass index(BMI), blood pressure, lab test...

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Published inZhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban Vol. 43; no. 5; p. 546
Main Authors Yu, Xin-yan, Zhao, Yi, Song, Xiao-xiao, Song, Zhen-ya
Format Journal Article
LanguageChinese
Published China 01.09.2014
Subjects
Alanine Transaminase
Body Mass Index
Humans
Incidence
Logistic Models
Non-alcoholic Fatty Liver Disease - epidemiology
Retrospective Studies
Risk Factors
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Summary:To investigate the association of body mass index (BMI) with alcoholic fatty liver disease (NAFLD). A cohort of 725 adult subjects underwent general health check-up at our hospital in July 2008, then were followed up in 2011. The clinical data including body mass index(BMI), blood pressure, lab testing results and liver ultrasonic findings were retrospectively analyzed. The NAFLD was diagnosed according to the guidelines for management of nonalcoholic fatty liver disease: an updated and revised edition in 2010 based on liver ultrasound results. The risk factors for NAFLD were analyzed with multivariate logistic regression. One hundred and sixty two NAFLD cases and 563 non-NAFLD cases were found in 2008 check-up. Among 563 non-NAFLD subjects, NAFLD was developed in 132 (23.4%) at follow-up in 2011. The incidence of NAFLD was correlated with the baseline BMI (χ²=82.861，P<0.01). Multivariate logistic regression analysis showed that baseline BMI，systolic blood pressure, alanine aminotransferase and the increase o
ISSN:1008-9292