Prognostic analysis of radical radiotherapy in stage Ib and IIa cervical carcinoma

To investigate the efficacy and prognostic factors in patients with stage Ib and IIa cervical carcinoma by radical radiotherapy. Between January 1999 and January 2012, 108 patients with stage Ib and IIa cervical carcinoma received radical radiotherapy in Cancer Hospital, Chinese Academy of Medical S...

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Published inChung-hua fu chʿan kʿo tsa chih Vol. 48; no. 9; p. 644
Main Authors Zeng, Jing, Zhang, Rong, Huang, Man, An, Ju-Sheng, Wu, Ling-Ying
Format Journal Article
LanguageChinese
Published China 01.09.2013
Subjects
Humans
Lymphatic Metastasis
Neoplasm Recurrence, Local
Neoplasm Staging
Prognosis
Uterine Cervical Neoplasms
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Summary:To investigate the efficacy and prognostic factors in patients with stage Ib and IIa cervical carcinoma by radical radiotherapy. Between January 1999 and January 2012, 108 patients with stage Ib and IIa cervical carcinoma received radical radiotherapy in Cancer Hospital, Chinese Academy of Medical Sciences were included and analyzed retrospectively. Patients of stage Ib1, Ib2, IIa1 and IIa2 were 18 (16.7%, 18/108), 38 (35.2%, 38/108), 33 (30.6%, 33/108) and 19 (17.6%, 19/108), respectively. The 5-year overall survival rate was 76.2% and the 5-year disease free survival rate was 75.6%. Totally 25 (23.1%, 25/108) patients developed recurrent disease, 16 of them (64%, 16/25) had local recurrences, 6 (24%, 6/25) had distant metastases and 3 cases had both local recurrence and distant metastases. Among patients with recurrent disease, 23 died and 2 survive with tumor. Totally 24 patients died, 23 of them died due to tumor recurrence and the other one died of other reason. The univariate analysis showed that, lymph
ISSN:0529-567X